DrML: Probabilistic Modeling of Gene Duplications
نویسندگان
چکیده
منابع مشابه
Modeling gene and genome duplications in eukaryotes.
Recent analysis of complete eukaryotic genome sequences has revealed that gene duplication has been rampant. Moreover, next to a continuous mode of gene duplication, in many eukaryotic organisms the complete genome has been duplicated in their evolutionary past. Such large-scale gene duplication events have been associated with important evolutionary transitions or major leaps in development an...
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Mutational robustness facilitates evolutionary innovations. Gene duplications are unique kinds of mutations, in that they generally increase such robustness. The frequent association of gene duplications in regulatory networks with evolutionary innovation is thus a special case of a general mechanism linking innovation to robustness. The potential power of this mechanism to promote evolutionary...
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ژورنال
عنوان ژورنال: Journal of Computational Biology
سال: 2014
ISSN: 1066-5277,1557-8666
DOI: 10.1089/cmb.2013.0078